Research Paper Volume 13, Issue 11 pp 15164—15192

Identification and validation of a novel eight mutant-derived long non-coding RNAs signature as a prognostic biomarker for genome instability in low-grade glioma

(A–B) Kaplan-Meier survival curves analysis for the eight genomic instability-associated lncRNAs using the training set (A) and validation set (B) of patients with low-grade glioma. (C–E) Nomograms for the eight genomic instability-associated lncRNAs for each factor in the training set, predictions of patient survival at 1, 3, and 5 years. Nomograms were evaluated using calibration curves and DCA curves. (F–H) Plot nomogram plots in the validation set and evaluation of nomograms using calibration curves and DCA curves.

Figure 5. (AB) Kaplan-Meier survival curves analysis for the eight genomic instability-associated lncRNAs using the training set (A) and validation set (B) of patients with low-grade glioma. (CE) Nomograms for the eight genomic instability-associated lncRNAs for each factor in the training set, predictions of patient survival at 1, 3, and 5 years. Nomograms were evaluated using calibration curves and DCA curves. (FH) Plot nomogram plots in the validation set and evaluation of nomograms using calibration curves and DCA curves.