Research Paper Volume 13, Issue 11 pp 15164—15192

Identification and validation of a novel eight mutant-derived long non-coding RNAs signature as a prognostic biomarker for genome instability in low-grade glioma

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Figure 8. Evaluation of the performance of the GILncSig partial gene using two external independent CGGA mRNA-seq-693 and GSE16011 datasets. (AB) Box plots for gene expression levels of AC064875.1 and H19 for patients at different ages (< = 41 and > 41 years), tumor grade, IDH1 mutation status, 1p19q chromosome union deletion status, gender and MGMT methylation status in patients from the CGGA mRNA-seq-693 set. (C) Box plots for expression of AC131097.4 for patients of different ages in the CGGA mRNA-seq-693 set. (D) Box plots for gene expression levels of FLG-AS1 for patients of different tumor grades and gender in the CGGA mRNA-seq-693 set. (E). Box plots expression level of lncRNA H19 in patients with different tumor grades and IDH1(R132) mutation status in the GSE16011 dataset.