Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 11 pp 15285—15306
Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer’s disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β-catenin pathway
Figure 7. BM-MSC-EVs activate the Wnt/β-catenin pathway via the miR-29c-3p/BACE1 axis. (A, B) RT-qPCR and WB were used to detect the effects of the miR-29c-3p/BACE1 axis on the mRNA expression and protein level of the Wnt/β-catenin pathway-related factors (Wnt3a and β-catenin) during EVs treating AD. The experiment was repeated three times, and the data were expressed as mean ± standard deviation. Data were analyzed using one-way ANOVA followed by Tukey’s multiple comparisons test. **p < 0.01; **p < 0.001.