Research Paper Volume 13, Issue 11 pp 15320—15335

Cistanche deserticola polysaccharides alleviate cognitive decline in aging model mice by restoring the gut microbiota-brain axis


Figure 1. Prolonged administration of D-galactose induces learning and memory impairment in mice. (A, B) Novel object recognition test results show preferential index values for WT and model group mice after (A) 24 h training and (B) 1 h testing phase. (CF) Morris water maze test results show (C) latency in learning phase, (D) latency in test phase, (E) number of plate crossings, and (F) time in the target quadrant for the WT and model group mice. Note: *p<0.05, **p<0.01, ***p<0.001 compared with the WT group mice; by. All values are represented as means ± SEM (n=15); Data was analyzed by one-way ANOVA followed by Dunnett's post hoc test.