Research Paper Volume 13, Issue 11 pp 15336—15352

Pharmacological targeting of TNS3 with histone deacetylase inhibitor as a therapeutic strategy in esophageal squamous cell carcinoma

TNS3 expression are relevant with tumorigenic properties of ESCC. (A) Clinical features of the 153 ESCC patients. (B) Representative IHC images of TNS3 in ESCC and the normal esophageal blocks. Scale bar = 100 μm. (C) Quantified staining scores of (B) (arbitrary units). (D) Correlations of TNS3 immunostaining scores with clinical TNM stage (upper) and histopathological grade (bottom) of ESCC, respectively. (E) The five years OS rate of ESCC patients with higher and lower levels of TNS3.

Figure 4. TNS3 expression are relevant with tumorigenic properties of ESCC. (A) Clinical features of the 153 ESCC patients. (B) Representative IHC images of TNS3 in ESCC and the normal esophageal blocks. Scale bar = 100 μm. (C) Quantified staining scores of (B) (arbitrary units). (D) Correlations of TNS3 immunostaining scores with clinical TNM stage (upper) and histopathological grade (bottom) of ESCC, respectively. (E) The five years OS rate of ESCC patients with higher and lower levels of TNS3.