Research Paper Volume 13, Issue 10 pp 13430—13442

Cognitive dedifferentiation as a function of cognitive impairment in the ADNI and MemClin cohorts

Sorted correlation strengths across all informative test pairs in the ADNI (n = 105) and MemClin (n = 190) datasets. Notice that inverse test scores (e.g. TMT) had been rescaled prior and that the assumption of positive manifold is slightly violated (a few negative correlations), possibly due to stochasticity. ADNI, Alzheimer’s Disease Neuroimaging Initiative; MemClin, Memory Clinic Project; CI, Cognitive Impairmen; NCI, No Cognitive Impairment; TMT, Trail-Making Test.

Figure 2. Sorted correlation strengths across all informative test pairs in the ADNI (n = 105) and MemClin (n = 190) datasets. Notice that inverse test scores (e.g. TMT) had been rescaled prior and that the assumption of positive manifold is slightly violated (a few negative correlations), possibly due to stochasticity. ADNI, Alzheimer’s Disease Neuroimaging Initiative; MemClin, Memory Clinic Project; CI, Cognitive Impairmen; NCI, No Cognitive Impairment; TMT, Trail-Making Test.