Figure 1. Characterization of thymic output (A) to the T-cell compartment and maturational subsets of CD4 (B) and CD8 (C) T-cells. The median and interquartile range (IQR) are shown. Categorical variables are expressed as the percentage of the number of cases. Subjects were classified according to a lower (1st tertile, <1.4), intermediate (2nd tertile, 1.4-2), or higher (3rd tertile, >2) CD4/CD8 ratio. Variables with a p-value <0.05 were considered statistically significant, as shown in bold. TREC, T-cell receptor excision circles; RTEs, recent thymic emigrants; CM, central memory; EM, effector memory; TemRA, terminally differentiated effector memory; ns, nonsignificant.