Figure 3. Characterization of the Treg subset. Frequencies (median and IQR) of Treg cells expressing Ki67 (A), OX40 (B), HLA-DR (C), and CTLA-4 (D). Subjects were classified according to a lower (1st tertile, <1.4), intermediate (2nd tertile, 1.4-2), or higher (3rd tertile, >2) CD4/CD8 ratio. Variables with a p-value <0.05 were considered statistically significant, as shown in bold. ns, nonsignificant.