Research Paper Volume 13, Issue 11 pp 14651—14674

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

Immunoblot validation of mRNA transcripts. (A) Selected mitochondrial proteins Mt-Atp6, Mt-Co2, Mt-Co-3 and (B) protein chaperons Hsp90A/B, Grp78, Calnexin and (C) mitochondrial quality control proteins Park2 and Pink1 and (D) neuroprotective Activin A and its antagonist Fst. Data are represented as mean ± S.E.M. n=5-7 mice in each experimental group. *P

Figure 5. Immunoblot validation of mRNA transcripts. (A) Selected mitochondrial proteins Mt-Atp6, Mt-Co2, Mt-Co-3 and (B) protein chaperons Hsp90A/B, Grp78, Calnexin and (C) mitochondrial quality control proteins Park2 and Pink1 and (D) neuroprotective Activin A and its antagonist Fst. Data are represented as mean ± S.E.M. n=5-7 mice in each experimental group. *P<0.05 compared with young Sham; **P<0.01 compared with young Sham; ***P<0.001 compared with young Sham.