Research Paper Volume 13, Issue 11 pp 14709—14728

The dysregulated Pink1- Drosophila mitochondrial proteome is partially corrected with exercise

Network analysis of differentially expressed proteins. (A) Pink1- exercised vs wild type exercised; (B) Pink1- non-exercised vs wild type non-exercised. Networks analysed using STRINGdb. The nodes are coloured according to the processes (legend) that the proteins are involved in by using GO Terms for Biological Processes. The edge shows type of interactions, experimentally determined interactions are pink and those obtained from databases are sky blue. Predicted interactions such as gene neighbourhood are blue, green and red for gene co-occurrence, gene neighbourhood and gene fusions. Co-expression interactions are shown in black, text-mining interactions are shown in light green and protein homology edges are purple.

Figure 5. Network analysis of differentially expressed proteins. (A) Pink1- exercised vs wild type exercised; (B) Pink1- non-exercised vs wild type non-exercised. Networks analysed using STRINGdb. The nodes are coloured according to the processes (legend) that the proteins are involved in by using GO Terms for Biological Processes. The edge shows type of interactions, experimentally determined interactions are pink and those obtained from databases are sky blue. Predicted interactions such as gene neighbourhood are blue, green and red for gene co-occurrence, gene neighbourhood and gene fusions. Co-expression interactions are shown in black, text-mining interactions are shown in light green and protein homology edges are purple.