Research Paper Volume 13, Issue 19 pp 22802—22829

Highly expressed centromere protein L indicates adverse survival and associates with immune infiltration in hepatocellular carcinoma

(A) Enrichment plots from GSEA. GSEA results showed that spliceosome, nucleotide excision repair, pyrimidine metabolism, DNA replication, ubiquitin mediated proteolysis, cell cycle, homologous recombination, mismatch repair, p53 signaling pathway and oocyte meiosis were significantly enriched in the high CENPL expression phenotype. GSEA: Gene Set Enrichment Analysis. (B) CENPL transcription level had prominent association with level of immune cell infiltration in HCC.

Figure 5. (A) Enrichment plots from GSEA. GSEA results showed that spliceosome, nucleotide excision repair, pyrimidine metabolism, DNA replication, ubiquitin mediated proteolysis, cell cycle, homologous recombination, mismatch repair, p53 signaling pathway and oocyte meiosis were significantly enriched in the high CENPL expression phenotype. GSEA: Gene Set Enrichment Analysis. (B) CENPL transcription level had prominent association with level of immune cell infiltration in HCC.