Research Paper Volume 13, Issue 19 pp 22843—22855

Figure 3. Allicin increased Cox-2, VEGF, myocardial LDH, and activated PI3K/AKT/mTOR pathway. (A) The immunofluorescence staining showed that compared with the Control group, the COX-2 positive area in the myocardial infarction area of Model group increased. Compared with the Model group, the myocardial LDH and COX-2 positive area was further significantly increased after Allicin treatment (^*P < 0.01). (B) Western blot analysis demonstrated that p-AKT, p-PI3K, p-mTOR, COX-2, and VEGF protein levels were also increased in the Allicin group compared to the Model (^*P < 0.01).