Research Paper Volume 13, Issue 19 pp 22649—22665

Effects of periostin deficiency on kidney aging and lipid metabolism

Gross appearance and renal function in young and aged WT and Postn-null mice. (A) Aged Postn-null mice had smaller body and kidney sizes than aged WT mice. Representative data are shown (N = 7/group) (bar: 1 cm). Data are the mean ± SEM. *p t-test). (B) Albuminuria and serum creatinine were reduced in aged Postn-null mice. Data are the mean ± SEM. *p t-test). (C) There was no difference in the survival rate between aged Postn-null mice and aged WT mice.

Figure 1. Gross appearance and renal function in young and aged WT and Postn-null mice. (A) Aged Postn-null mice had smaller body and kidney sizes than aged WT mice. Representative data are shown (N = 7/group) (bar: 1 cm). Data are the mean ± SEM. *p < 0.05 (unpaired t-test). (B) Albuminuria and serum creatinine were reduced in aged Postn-null mice. Data are the mean ± SEM. *p < 0.05 (unpaired t-test). (C) There was no difference in the survival rate between aged Postn-null mice and aged WT mice.