Research Paper Volume 13, Issue 19 pp 22912—22933

Significance of CD8+ T cell infiltration-related biomarkers and the corresponding prediction model for the prognosis of kidney renal clear cell carcinoma

Genetic landscape analysis of mutation and copy number variation (CNV) in high and low TIL-CD8Sig score groups. (A) Mutation waterfall graph of different TIL-CD8Sig score subgroups in the TCGA-KIRC cohort. (B) CNV spectrum of different TIL-CD8Sig score subgroups in the TCGA-KIRC cohort. Different colors represent different CNV types (gain or loss); the abscissa axis represents chromosome locus; the ordinate axis represents CNV frequency. (C) The difference of mutation frequency in different TIL-CD8 Sig score subgroups. The abscissa axis represents different scoring groups; the ordinate axis represents mutation frequency.

Figure 4. Genetic landscape analysis of mutation and copy number variation (CNV) in high and low TIL-CD8Sig score groups. (A) Mutation waterfall graph of different TIL-CD8Sig score subgroups in the TCGA-KIRC cohort. (B) CNV spectrum of different TIL-CD8Sig score subgroups in the TCGA-KIRC cohort. Different colors represent different CNV types (gain or loss); the abscissa axis represents chromosome locus; the ordinate axis represents CNV frequency. (C) The difference of mutation frequency in different TIL-CD8 Sig score subgroups. The abscissa axis represents different scoring groups; the ordinate axis represents mutation frequency.