Research Paper Volume 13, Issue 19 pp 22963—22984

RUNX2 and LAMC2: promising pancreatic cancer biomarkers identified by an integrative data mining of pancreatic adenocarcinoma tissues

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Figure 1. Identification of DEGs, DEMs and key genes. (A) The volcano plot of mRNA GEO datasets GSE62165, GSE15471 and GSE32676 respectively; (B) Venn diagram of up-regulated DEGs and down-regulated DEGs set from GSE62165, GSE15471 and GSE32676 datasets; (C) The volcano plot of miRNA GEO datasets GSE24279 and GSE32678 respectively; (D) Venn diagram of up-regulated DEMs and down-regulated DEMs set from GSE24279 and GSE32678 datasets; (E) The target genes, tDEMTGs, of 66 consistent DEMs (tDEMs) were predicted by miRTarBase, miRWalk and Diana Tools databases. (F) Venn diagram of tDEMTGs and tDEGs to get key genes.