Research Paper Volume 13, Issue 19 pp 22963—22984

RUNX2 and LAMC2: promising pancreatic cancer biomarkers identified by an integrative data mining of pancreatic adenocarcinoma tissues

Verification of key genes. (A) RUNX2, LAMC2 and FXBO32 expression levels (Log2FoldChange value) in GSE14245, GSE74629, GSE49641, GSE49515 and GSE15932. (B) Representative immunohistochemistry staining of RUNX2 and LAMC2 in pancreatic ductal adenocarcinoma (PC tissue) and control pancreatic tissue (Normal tissue) in Human Protein Atlas (HPA). Scales bars represent 200 μm. (C) Western blot analysis for RUNX2 and LAMC2 expression proteins in 16 paired samples from PC patients.

Figure 5. Verification of key genes. (A) RUNX2, LAMC2 and FXBO32 expression levels (Log2FoldChange value) in GSE14245, GSE74629, GSE49641, GSE49515 and GSE15932. (B) Representative immunohistochemistry staining of RUNX2 and LAMC2 in pancreatic ductal adenocarcinoma (PC tissue) and control pancreatic tissue (Normal tissue) in Human Protein Atlas (HPA). Scales bars represent 200 μm. (C) Western blot analysis for RUNX2 and LAMC2 expression proteins in 16 paired samples from PC patients.