Research Paper Volume 13, Issue 19 pp 23193—23209

Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome

Schisandrin B presented colitis in mice model. (A) DAI score; (B) weight of mice; (C) HE staining results of colon (×200); (D) Colon macroscopic score. ##P

Figure 1. Schisandrin B presented colitis in mice model. (A) DAI score; (B) weight of mice; (C) HE staining results of colon (×200); (D) Colon macroscopic score. ##P<0.01 vs control group; **P<0.01 vs DSS- induced colitis group. Control: blank control group; Colitis: DSS- induced colitis group; Colitis+SCH: Schisandrin was used to treat DSS- induced colitis. SCH, Schisandrin B. Data were expressed as mean ± SEM.