Research Paper Volume 13, Issue 19 pp 23210—23232

Integrated analysis of tumor-associated macrophage infiltration and prognosis in ovarian cancer

Identification of the molecular subtypes based on 219 TAMRG signatures. (A) CDF plot of the consensus score (k = 2–6). (B) Consensus clustering matrix for k = 2. (C) Heatmap showing differentially expressed genes between the two groups. (D) Kaplan–Meier analysis of overall survival for clusters 1 and 2. (E) The TAM abundance of two groups is shown in violin plots. (F) Upregulated pathways in GSEA. (G) The expression of six immune checkpoints between the two molecular subtypes.

Figure 6. Identification of the molecular subtypes based on 219 TAMRG signatures. (A) CDF plot of the consensus score (k = 2–6). (B) Consensus clustering matrix for k = 2. (C) Heatmap showing differentially expressed genes between the two groups. (D) Kaplan–Meier analysis of overall survival for clusters 1 and 2. (E) The TAM abundance of two groups is shown in violin plots. (F) Upregulated pathways in GSEA. (G) The expression of six immune checkpoints between the two molecular subtypes.