Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Yi Yang; Xiaodong Gu; Zhenyang Li; Chuang Zheng; Zihao Wang; Minwei Zhou; Zongyou Chen; Mengzhen Li; Dongbing Li; Jianbin Xiang

doi:doi:10.18632/aging.203618

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Research Paper Volume 13, Issue 19 pp 23262—23283

Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Figure 11. Potential driver genes related to LRRC. Forty-eight genes included (1) genes reported as significantly mutated genes in the previous study in CRC; (2) genes with a higher mutation rate in the cohort (TCGA Freq≥10%; MSK Freq≥5%).