Research Paper Volume 13, Issue 19 pp 23262—23283

Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Potential driver genes related to LRRC. Forty-eight genes included (1) genes reported as significantly mutated genes in the previous study in CRC; (2) genes with a higher mutation rate in the cohort (TCGA Freq≥10%; MSK Freq≥5%).

Figure 11. Potential driver genes related to LRRC. Forty-eight genes included (1) genes reported as significantly mutated genes in the previous study in CRC; (2) genes with a higher mutation rate in the cohort (TCGA Freq≥10%; MSK Freq≥5%).