Research Paper Volume 13, Issue 19 pp 23284—23307

Transcriptome research identifies four hub genes related to primary myelofibrosis: a holistic research by weighted gene co-expression network analysis

(A) Cluster dendrogram of all genes enriched based on the dissimilarity measure and the assignment modules. Highly interconnected groups of genes were clustered. Every color below represented one co-expression module, totally 14 distinct modules were identified with the hierarchical clustering tree analysis. (B) Topological overlap heatmap of the gene co-expression network. Each row and column represented a gene. Light color indicated high topological overlap and dark color represented low topological overlap. Different colors on x and y axis indicated different modules. The dendrogram suggested that the clustering of these genes was based on the similarity of their gene expression levels.

Figure 3. (A) Cluster dendrogram of all genes enriched based on the dissimilarity measure and the assignment modules. Highly interconnected groups of genes were clustered. Every color below represented one co-expression module, totally 14 distinct modules were identified with the hierarchical clustering tree analysis. (B) Topological overlap heatmap of the gene co-expression network. Each row and column represented a gene. Light color indicated high topological overlap and dark color represented low topological overlap. Different colors on x and y axis indicated different modules. The dendrogram suggested that the clustering of these genes was based on the similarity of their gene expression levels.