Research Paper Volume 13, Issue 19 pp 23284—23307

Transcriptome research identifies four hub genes related to primary myelofibrosis: a holistic research by weighted gene co-expression network analysis

(A) Summary plot of different machine learning models. (B) ROC curves of support vector machine. (C–E) 3D scatter plot after principal component analysis of hub genes. (F) Expression values of hub genes between different groups in GSE53482. (G) Expression values of hub genes between different groups in GSE61629. ***: P  0.05. (H) Expression of the hub genes EPB42, CALR, SLC4A1, MPL between PMF patients and healthy donors collected at our institution.

Figure 9. (A) Summary plot of different machine learning models. (B) ROC curves of support vector machine. (CE) 3D scatter plot after principal component analysis of hub genes. (F) Expression values of hub genes between different groups in GSE53482. (G) Expression values of hub genes between different groups in GSE61629. ***: P < 0.001, **: P < 0.01, *: P < 0.05, ns: P> 0.05. (H) Expression of the hub genes EPB42, CALR, SLC4A1, MPL between PMF patients and healthy donors collected at our institution.