Research Paper Volume 13, Issue 19 pp 23308—23327

Transcriptome and proteome analysis of the antitumor activity of maslinic acid against pancreatic cancer cells

MA-induced apoptosis of pancreatic cancer cells. (A) Flow cytometry detection of the apoptosis of PANC-1 and Patu-8988 cells exposed to MA for 24 h, analyzed by Annexin V/PI staining. (B) Western blot analysis showing the expression of cleaved-caspase3 in MA-treated PANC-1 and Patu-8988 cells. Data are representative of three independents experiments and expressed as mean ± SD. *p

Figure 3. MA-induced apoptosis of pancreatic cancer cells. (A) Flow cytometry detection of the apoptosis of PANC-1 and Patu-8988 cells exposed to MA for 24 h, analyzed by Annexin V/PI staining. (B) Western blot analysis showing the expression of cleaved-caspase3 in MA-treated PANC-1 and Patu-8988 cells. Data are representative of three independents experiments and expressed as mean ± SD. *p <0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.