Research Paper Volume 13, Issue 20 pp 23527—23544

NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants


Figure 1. Illustration of different perinatal age metrics, measured in weeks and days, which we highlight for infants born preterm. Gestational age (GA) is defined as the time from conception to birth (expected delivery around 37-42 weeks typically refers to full-term birth, and <37 weeks refers to preterm birth). Post-menstrual age (PMA) refers to the time from conception onward, and postnatal age (PNA) is equivalent to chronological age and is the time elapsed after birth. In this study, buccal cell tissue was collected from infants at NICU discharge to profile DNA methylation.