Research Paper Volume 13, Issue 20 pp 23739—23756

Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer’s disease

The intricate PPI network of the differentially expressed proteins and selected functional categories. This network and functional categories were conducted and visualized among the dysregulated proteins in the hippocampus of the 3xTg-AD mice treated with loganin compared with the control mice. Red expressed up-regulated and green expressed down-regulated. The brighter the image, the greater the fold change.

Figure 6. The intricate PPI network of the differentially expressed proteins and selected functional categories. This network and functional categories were conducted and visualized among the dysregulated proteins in the hippocampus of the 3xTg-AD mice treated with loganin compared with the control mice. Red expressed up-regulated and green expressed down-regulated. The brighter the image, the greater the fold change.