Research Paper Volume 13, Issue 24 pp 25859—25885

Identification and functional analysis of lncRNAs and mRNAs between tumorigenesis and metastasis in CRC


Figure 5. Functional analysis of lncRNAs in CRC metastasis. (A) lncRNA-mRNA network in CRC metastasis: 10 selected lncRNAs and 53 mRNAs were included in the network. (B) GO term network Each term is represented by a circle node, where its size is proportional to the number of input genes falling into that term, and its color represents its cluster identity. (C) Top three MCODE networks for differentially expressed lncRNA-associated mRNAs. (D) GO enrichment showed differentially expressed lncRNA-associated biological processes (top 10). (E) KEGG pathway analysis showed differentially expressed lncRNA-associated signaling pathways (top 10).