Research Paper Volume 13, Issue 24 pp 25653—25669

Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children

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Figure 2. Forest plots of model coefficients and 95% CI for methylation-based aging biomarkers by ACE domains. Figure 2 presents forest plots of model coefficients and 95% CIs for child methylation-based age biomarkers (EAA Horvath (A), IEAA (B), and DNAmTL Age Adjusted (C)) across all three CHAMACOS participant age timepoints for individual ACE domains (Obs = 483). Methylation-based age biomarkers are those with statistically significant associations with cumulative ACE scores.