Research Paper Volume 13, Issue 24 pp 25694—25716

Age-dependent expression changes of circadian system-related genes reveal a potentially conserved link to aging


Figure 3. Heatmap representing log2 fold changes of the CR-related genes for the species, tissues and age categories investigated. DEG up-regulations in the course of aging are indicated by positive values displayed in blue, whereas down-regulations are shown by negative values in red. Significant gene expression alterations are highlighted in bold. The abbreviation longe. stands for the longevity age comparison (aged vs. old-age samples). For details, see the online supplement