Research Paper Volume 13, Issue 24 pp 25694—25716

Age-dependent expression changes of circadian system-related genes reveal a potentially conserved link to aging


Figure 5. Age-dependent alterations in the robustness of CR-related gene expression. For the 3 age comparisons, different tissues, and species, the measured variance in the expression of CR-related genes is displayed as change in standard deviation. The extrema of the box plots represent the respective 2.5% percentiles. Age groups (M – mature, A – aged, OA – old-age) are compared for their statistical significance: *p-value ≤ 0.01, **p-value ≤ 0.001, ***p-value ≤ 0.0001. Details can be found in the online supplement: