Research Paper Volume 13, Issue 24 pp 25739—25762

Small molecules for cell reprogramming: a systems biology analysis


Figure 4. The network with the highest interconnectivity (corresponding to the TLT cocktail). In total, 58 protein targets are in the network. Continuous network without taking into account drug connectivity (chemical-protein interactions) includes 44 genes/proteins (75.9%; values for random sampling (mean ± SD): 4.5 ± 2.4; z-score for observed value: 30.03).