Research Paper Volume 13, Issue 24 pp 26095—26117

Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors


Figure 3. Hsa_circ_0063526 and miR-141-5p expression level is negative correlated. (A) Quantitative analysis of miR-141-5p expression levels in endometriosis group and control group by RT-qPCR.n=41 (** P<0.01). (B) Pearson’s correlation analysis of the correlation between hsa_circ_0063526 and miR-141-5p expression level in the endometriosis group. n=31(P<0.05) (C) RT-qPCR shows the relative expression level of hsa_circ_0063526 in End1/E6E7 cells after downregulation of hsa_circ0063526 or inhibition of miR-141-5p. (**** P<0.001). (D) RT-qPCR shows the relative expression level of miR-141-5p in End1/E6E7 cells after down-regulation of hsa_circ_0063526. (*(P<0.05, ** P<0.01). Replicated 3 times with 3 separate samples.