Research Paper Volume 13, Issue 24 pp 26148—26160

Free fatty acids-induced neutrophil extracellular traps lead to dendritic cells activation and T cell differentiation in acute lung injury


Figure 6. Inhibitors reduced the formation of NETs induced by OA. (A) Effect of DPI, U0126, SB202190, and SP600125 on OA-induced formation of NETs. (B) Effect of DNase I on OA-induced formation of NETs. Abbreviations: OA: oleic acid; NETs: neutrophil extracellular traps; DPI: NADPH oxidase inhibitor; DNase I: NETs inhibitor; SB202190: p38-specific inhibitor; U0126: ERK1/2-specific inhibitor; SP600125: JNK-specific inhibitor. *P < 0.05, **P < 0.01, and ***P < 0.001, respectively.