Research Paper Volume 13, Issue 24 pp 26148—26160

Free fatty acids-induced neutrophil extracellular traps lead to dendritic cells activation and T cell differentiation in acute lung injury


Figure 7. FFAs induced NETs promote the activation of DCs. (A) DCs stimulated with NETs could increase the expression of CD40, CD86 and HLA-DR. (B) DCs stimulated with NETs could improve the release level of IL-1β, IL-12 and TNF-α. (C) DCs stimulated with NETs could promote the differentiation of primary CD4+ T into Th1 and Th17 cells. Abbreviations: FFAs: free fatty acids; NETs: neutrophil extracellular traps; DCs: dendritic cells. **P < 0.01 and ***P < 0.001.