Coupling of serum CK20 and hyper-methylated <i>CLIP4</i> as promising biomarker for colorectal cancer diagnosis: from bioinformatics screening to clinical validation

Zhongjian Liu; Hui Tang; Wen Zhang; Jinli Wang; Lilan Wan; Xisha Li; Yuping Ji; Na Kong; Yanfang Zhang; Jiangang Wang; Zhang Fan; Qiang Guo

doi:doi:10.18632/aging.203804

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Research Paper Volume 13, Issue 24 pp 26161—26179

Coupling of serum CK20 and hyper-methylated CLIP4 as promising biomarker for colorectal cancer diagnosis: from bioinformatics screening to clinical validation

Figure 8. The expression of CLIP4 in tumor tissues and cancer cell lines and the methylation status of CLIP4 in CRC tissues. The mRNA expression of CLIP4 in certain tumor tissues and CRC tissues was analyzed by GEPIA. The methylation level of CLIP4 in CRC and normal tissues was analyzed by UALCAN. Abbreviations: COAD: colon adenocarcinoma; READ: rectum adenocarcinoma.