Research Paper Volume 14, Issue 2 pp 747—769

Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma


Figure 1. CCT7 levels in HCC and adjacent normal liver tissues. (A) CCT7 mRNA levels were significantly greater in HCC than in normal liver tissues. (B, C) CCT7 mRNA expression increased incrementally with increasing cancer stages (B) and tumor grades (C) in HCC tissues. (D) CCT7 mRNA levels were greater in metastatic than in non-metastatic tumor samples. (E, F) Higher CCT7 mRNA expression was associated with worse OS (E) and RFS (F). (GI) Representative images from immunohistochemical staining of CCT7 protein expression in normal liver tissues (G, expression quantity <25%), low-expression HCC tissues (H, expression quantity 25–50%) and high-expression HCC tissues (I, expression quantity >75%) from the Human Protein Atlas database.