Research Paper Volume 14, Issue 1 pp 354—367

Telomere length is maternally inherited and associated with lipid metabolism in Chinese population


Figure 3. Knockdown of genes for lipid metabolism shortened telomere length (TL) in HepG2 cells. PNPLA2 and CPT1 genes were knocked down by short-hairpin RNA (shRNA) in HepG2 cells. (A) Efficiency of gene knockdown by short-hairpin RNA (shRNA) was evaluated by qPCR. (B) Oil red O staining in HepG2 cells after PNPLA2 and CPT1 knockdown by shRNA. (C) TL was determined by qPCR in HepG2 cells. Data were expression as mean±SEM. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.