**Figure 5.** **Identification of DEGs and functional enrichment analysis of DEGs.** (**A**) Volcano plot of differential gene profiles between CHRDL1-high and -low groups. A total of 501 DEGs (241 upregulated and 260 downregulated) were identified. (**B**) Enriched GO terms in the "Biological Process" category. (**C**) Enriched GO terms in the "Cellular Component" category. (**D**) Enriched GO terms in the "Molecular Function" category. (**E**) Enriched GO terms in the "KEGG Pathway" category. The x-axis represents the proportion of DEGs, and the y-axis represents different categories. The colors indicate adjusted P-value, and the column lengths and circle sizes represent the enriched number of DEGs.