Research Paper Volume 14, Issue 3 pp 1265—1279

Hesperidin suppresses ERS-induced inflammation in the pathogenesis of non-alcoholic fatty liver disease


Figure 1. HSP suppressed HFD-induced body weight gain and hepatic steatosis but not serum lipid profile. SD rats were fed with CD or HFD for 4 months and were randomly divided into CD + NS group, CD + HSP group, HFD + NS group, and HFD + HSP group. (A) The body weight of the rat was evaluated. Data were presented as mean ± SEM. **P < 0.05. (B) The levels of serum TC, TG, and LDL, FFA were examined (C) the levels of serum IL-1β, IL-6, TNF-α. Data were presented as mean ± SEM. (D) Histological analysis of hepatic steatosis stained with Oil Red O staining.