Research Paper Volume 14, Issue 3 pp 1265—1279

Hesperidin suppresses ERS-induced inflammation in the pathogenesis of non-alcoholic fatty liver disease


Figure 6. HSP attenuates ERS in human THP-1 cells. As described in the method, FFA-stimulated human THP-1 cells were employed to establish the NAFLD model. Thapsigargin was used to simulate the in vitro ERS model. (A) Immunofluorescence staining was performed to examine the expression of GRP94 and p-PERK with or without HSP. (B) Relative fluorescence intensity of GRP94 and p-PERK. Data were presented as mean ± SEM. **P < 0.05, FFA + HSP vs. FFA.