**Figure 1.** **Circ_0000515 expression was greatly raised in BC tissues and cell lines.** (**A**) Volcanic plot showed the differentially expressed circRNAs in BC tumor tissues and adjacent tissues. (**B**) Heat map showed some representative ascended circRNAs in BC tumor tissues. (**C**, **D**) qRT-PCR ensured the analysis of circ_0000515 expressions in BC tissues and cell lines.****P*<0.001.