Research Paper Volume 14, Issue 1 pp 225—239

Dietary curcumin restores insulin homeostasis in diet-induced obese aged mice


Figure 4. Curcumin supplementation raised insulin sensitivity by IDE expression. (A) 6-hours fasting insulin levels (ng/mL) at week 15 (n = 5-7). (B) Insulin Tolerance Test (ITT) was performed for 14 weeks after diet treatment, and the area under the curve (AUC) analysis (n = 4-8). (C) IDE and GAPDH protein expression levels in liver tissue lysate 15 weeks after diet treatment (n=3) (D) IDE and β-actin protein expression levels in primary hepatocytes 15 weeks after diet treatment (n=4) (E) fasting plasma IDE (ng/mL) basal level and 15 weeks after diet treatment (n = 5-7). *p ≤ 0.05 and **p ≤ 0.01.