**Figure 5.** **Construction of risk signature in the TCGA cohort.** (**A**) Univariate cox regression analysis of OS. (**B**) LASSO regression of OS-related genes. (**C**) Cross-validation for tuning the parameter selection. (**D**) Risk survival status plot. (**E**) Kaplan–Meier curve result. (**F**) The AUC of the prediction of 1, 3, 5-year survival rate of PAAD. (**G**) PCA plot. (**H**) t-SNE plot.