Research Paper Volume 14, Issue 3 pp 1307—1320

Inhibiting effect of miR-29 on proliferation and migration of uterine leiomyoma via the STAT3 signaling pathway


Figure 3. STAT3 as the hub genes for uterine leiomyoma, and the association between miR-29 and STAT3. (A) Protein-protein interaction (PPI) network. (B) STAT3 was in the powerful module through the Molecular Complex Detection tool (MCODE) analysis. (C) A Venn diagram was drawn to identify the common miRNA (miR-29c-3p) among the TargetScan, miRDB, and GSE5244. (D) predicted consequential pairing of the target region of STAT3 and miR-29C-3p. (E) compared with the control group, the expression of miR-29c was lower in the uterine leiomyoma.