Research Paper Volume 14, Issue 3 pp 1321—1335

CTRP3 alleviates cardiac ischemia/reperfusion injury via LAMP1/JIP2/JNK signaling pathway


Figure 7. Overexpression of CTRP3 ameliorated I/R injury. (A, B) The levels of LVEF and LVFS were detected by echocardiograph as indexes for cardiac function at the end of the 24 h reperfusion. (C) Representative images of stained myocardial tissues of mice in all groups. (D) The percentage of myocardial infarction area of all groups. (E, F) Cardiomyocyte apoptosis was determined by using TUNEL assay. (GI) The production of ROS, MDA and cTn-I was determined. (J, K) Western blotting was performed to analyze the protein expression of CTRP3, LAMPA, JIP2, JNK and p-JNK in myocardial tissue.