Figure 2. Genomic difference analyses and PPI network construction. (A–D) The volcano plots showing the differentially-expressed genes between the sham-operated and CRS model rats in week 2 (A), week 4 (B), week 5 (C), and week 7 (D). (E) A sum of 35 differentially expressed genes were overlapped. (F) The PPI network of the 35 genes. (G) The Top 10 genes with the highest degree value in the network. Abbreviation: PPI: protein-protein interaction network.