Research Paper Volume 14, Issue 3 pp 1214—1232

Ribosomal DNA methylation in human and mouse oocytes increases with age


Figure 1. Methylation of oppositely imprinted regions in individual human oocytes. Mean methylation of PEG3 (red dots) and GTL2 (green dots) in 174 individual human GV oocytes included in this study. Only oocytes with correct oocyte methylation of at least one of the two analyzed imprinted genes were taken for further analysis. The vast majority (88%) of oocytes display correct methylation for both controls.