Research Paper Volume 14, Issue 3 pp 1214—1232

Ribosomal DNA methylation in human and mouse oocytes increases with age


Figure 2. rDNA methylation difference between oocytes from younger versus older women. Box plots showing the rDNA core promoter and rDNA UCE methylation in younger women (26-32 years; N = 42) and older women (33-39 years; N = 48). The median is represented by a horizontal line. The bottom of the box indicates the 25th percentile, the top the 75th percentile. Outliers are shown as circles and extreme outliers as stars. The methylation levels in the older group are higher compared to the younger group.