Research Paper Volume 14, Issue 4 pp 1767—1781

The novel lncRNA GPC5-AS1 stabilizes GPC5 mRNA by competitively binding with miR-93/106a to suppress gastric cancer cell proliferation


Figure 4. GPC5 suppresses GC cell proliferation and induces apoptosis. (A, B) Expression levels of GPC5 in GC tissues and their paired normal tissues according to the TCGA database. (C, D) Protein expression of GPC5 was measured by western blot and immunohistochemistry in randomly selected GC tissue samples. (E) Colony formation, (F) MTT assay, (G) cell cycle, and (H) cell apoptosis assay were performed in SGC-7901 cells with Ov-GPC5. (IL) Cell function analyses were determined in BGC-823 cells with Ov-GPC5. (p* < 0.05, p** < 0.01).