Research Paper Volume 14, Issue 4 pp 1891—1909

Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway


Figure 4. miR-942 plays an oncogenic role and is sponged by circSHPRH in BCa. (A) Comparison of miR-942 expression between BCa tissues and normal tissues from the TCGA dataset. (B) Expression of miR-942 in BCa based on TP53 mutation status analyzed by the UALCAN web server. (C) The relative expression of miR-942 in 28 BCa tissues and paired normal tissues, as measured by qRT–PCR. (D) Correlation between miR-942 and circSHPRH expression in BCa tissues by qRT–PCR. (E, F) Silencing miR-942 abrogated the cell migration (E) and invasion (F) abilities induced by circSHPRH knockdown.*P<0.05, **P<0.01, ****P<0.0001.