Research Paper Volume 14, Issue 4 pp 1891—1909

Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway


Figure 8. circSHPRH knockdown activates the Wnt/β-catenin signaling pathway by regulating BARX2. (A, B) Relative expression of BARX2, β-catenin and c-MYC in T24 and UM-UC-3 cells transfected with vector or BARX2 plasmid. (CF) Rescue assays indicated that the promoting effect of circSHPRH knockdown on c-MYC and nuclear β-catenin expression was partially diminished by BARX2 overexpression in T24 (C, D) and UM-UC-3 cells (E, F).*P<0.05, **P<0.01.