Research Paper Volume 14, Issue 4 pp 1891—1909

Circular RNA circSHPRH inhibits the malignant behaviors of bladder cancer by regulating the miR-942/BARX2 pathway


Figure 9. Overexpression of circSHPRH represses tumor growth in vivo. (A) Representative images of subcutaneous tumors in BALB/c nude mice. (B) The tumor volume of xenograft tumors at different time points. (C) Representative images of dissected tumors from sacrificed mice. (D) Compared with the control group, the tumor weights significantly decreased in the circSHPRH-overexpressing group. (E) Schematic diagram shows that circSHPRH inhibits BCa cells proliferation and migration through the miR-942/BARX2/Wnt/β-catenin signaling pathway.